問7 ベンゾジアゼピン骨格

問7 ベンゾジアゼピン骨格

- 野中 孝昌 の投稿

\spc\sixheterov[ace]{2s==\tetramethylene{4==\upnobond{N}{H}}{1==(yl);3D==O}}{}[]\put(65,400){\fourhetero[]{3s==\xFiveCycle(0,0){-90}[]{1==N;4s==\exosinglebond{-25};4s==\exosinglebond{25};33==S}[a]}{4D==O;1SA==;1FB==H;2GB==H}[]\put(270,380){\sffamily\bfseries CH$\bf_3$}\put(270,240){\sffamily\bfseries CH$\bf_3$}\adddash(-5,500)(-1,2){68}\put(-140,630){\sffamily\bfseries H}\WedgeAsSubstX(-5,505)(80,620)\put(65,630){\sffamily\bfseries CO$\bf_2$K}}　ベンジルペニシリンカリウム

\sixheterov[ace]
{2s==\tetramethylene{4==\upnobond{N}{H}}{1==(yl);3D==O}}
{}[]
\put(50,400){
\fourhetero[]
{3s==\xFiveCycle(0,0){-90}[]{1==N;4s==\exosinglebond{-25};4s==\exosinglebond{25};33==S}[a]}
{4D==O;1SA==;1FB==H;2GB==H}[]
\put(270,380){\sffamily\bfseries CH$\bf_3$}
\put(270,240){\sffamily\bfseries CH$\bf_3$}
\adddash(-5,500)(-1,2){68}
\put(-140,630){\sffamily\bfseries H}
\WedgeAsSubstX(-5,505)(80,620)
\put(65,630){\sffamily\bfseries CO$\bf_2$K}
}

\trimethylenei{1==H$\bf_3$C;2==O;3s==\sixheterov[bdf,{B\xFiveCycle(0,0){-18}[b]{3s==\exosinglebond{-72};4==N}[e]}]{4s==\put(360,48){\rotatebox{-12}{\sixheteroh[]{5==}{1==(yl)}[abcd]}};4s==\put(600,-220){CO$\bf_2$H};2s==\put(-85,-280){\decaheterovt[acK]{6==\put(150,-80){CH$\bf_3$};7==}{3==Cl;8D==O}[efg]}}{5==(yl)}[]}{}　インドメタシン

\trimethylenei{1==H$\bf_3$C;2==O;
3s==\sixheterov[bdf,
{B\xFiveCycle(0,0){-18}[b]{3s==\exosinglebond{-72};4==N}[e]}]{4s==\put(360,48){\rotatebox{-12}{\sixheteroh[]{5==}{1==(yl)}[abcd]}};4s==\put(600,-220){CO$\bf_2$H};
2s==\put(-85,-280){
\decaheterovt[acK]{6==\put(150,-80){CH$\bf_3$};7==}{3==Cl;8D==O}[efg]
}
}{5==(yl)}[]}{}

\put(635,800){\exosinglebond{-154}\put(-40,5){\sffamily\bfseries H}}\sixheterov[bdf,{B\SevenCycle(0,0){-38}[b]{2s==\exosinglebond{-154};3==N;5s==\exodoublebond{0};6==N}[g]}]{1s==\put(590,90){O}}{5==O$\bf_2$N}[]\put(-693,-655){\rotatebox{20}{\bzdrh[l]{}}}　ニトラゼパム

\put(635,800){
\exosinglebond{-154}
\put(-40,5){\sffamily\bfseries H}
}
\sixheterov[bdf,{B\SevenCycle(0,0){-38}[b]{2s==\exosinglebond{-154};3==N;5s==\exodoublebond{0};6==N}[g]}]{1s==\put(590,90){O}}{5==O$\bf_2$N}[]
\put(-693,-655){\rotatebox{20}{\bzdrh[l]{}}}

\spc\sixheterov[bdf]{2s==\sixheterov[]{2s==\sixheterov[]{5==;2s==\sixheterov[]{1==N;2==CH$_{\bf 3}$;3==Cl}{1==CH$_{\bf 3}$;6==(yl)}[bde]}{4==(yl)}[bcd];1==N;4==S;2s==\sixheterov[ace]{}{6==(yl)}[e]}{6==(yl)}[e]}{}[]　クロルプロマジン

\sixheterov[bdf]{
2s==\sixheterov[]{
2s==\sixheterov[]{5==;
2s==\sixheterov[]{1==N;2==CH$_{\bf 3}$;3==Cl}{1==CH$_{\bf 3}$;6==(yl)}[bde]}{4==(yl)}[bcd];1==N;4==S;
2s==\sixheterov[ace]{}{6==(yl)}[e]}{6==(yl)}[e]}{}[]

\sixheteroh[ace]{5s==\PutBondLine(0,0)(160,-80){0.85pt};3s==\sixheteroh[]{5s==\WedgeAsSubst(0,0)(1,0){200};3s==\PutBondLine(130,170)(202,170){0.8pt};4s==\sixheteroh[]{2s==\textcolor{white}{\PutBondLine(97,-50)(97,50){2pt}};2s==\PutBondLine(97,-168)(97,342){0.8pt};}{2==(yl);2FB==HO;5D==O;6Su==H;6Sd==\lmoiety{O\,}}[a];3s==\put(-300,120){\sixheterov[b]{2==CH$\bf_2$}{4==}[adef]}}{1==(yl);3FA==H;3B==N}[f]}{6==\lmoiety{HO}}[]　ナロキソン

\sixheteroh[ace]{5s==\PutBondLine(0,0)(160,-80){0.85pt};
3s==\sixheteroh[]{5s==\WedgeAsSubst(0,0)(1,0){200};3s==\PutBondLine(130,170)(202,170){0.8pt};
4s==\sixheteroh[]{2s==\textcolor{white}{\PutBondLine(97,-50)(97,50){2pt}};2s==\PutBondLine(97,-168)(97,342){0.8pt};}{2==(yl);2FB==HO;5D==O;6Su==H;6Sd==\lmoiety{O\,}}[a];
3s==\put(-300,120){\sixheterov[b]{2==CH$\bf_2$}{4==}[adef]}}{1==(yl);3FA==H;3B==N}[f]}{6==\lmoiety{HO}}[]