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問207 ラベプラゾールの代替薬品

粉砕して服用する場合の不都合を回避するために、当該病院の採用薬の中から薬剤師が提案する薬物として、適切でないのはどれか。1 つ選べ。ただし、これらの薬剤は全て錠剤であり粉砕して用いるものとする。


\tetramethylenei{1==H$\bf_3$C;2==N;
4s==\FiveCycle(-65,189){0}[be]{4==O;
3s==\heptamethylene{3==S;6==\upnobond{N}{H};
7s==\sixheterov[f]{1s==\hspace{-1mm}*;2==NO$\bf_2$;5==\put(-70,0){NH}}{5==H$\bf_3$C;6==(yl)}[bcd]
}{1==(yl)}
}[]
}{2==CH$\bf_3$}
\put(1150,-250){\text{及び{\sffamily\bfseries C}*位幾何異性体}}

\decaheterov
[egi,{B\FiveCycle(0,0){-18}[bd]{1==\hspace{2mm}\phantom{.};
3s==\rotatebox{40}{\sixfusev[]
{5s==\rotatebox{-30}{\sixfuseh[ace]{}{3==\rotatebox{9}{F}}{b}[]}}
{}{F}[abcf]};
4s==\rotatebox{22}{\sixfuseh[]{3==\rotatebox{-4}{NH}}{3==\rotatebox{-4}{CH$\bf_3$}}{F}[cde]}
}[e]}]
{3==N;6==N;4s==\hspace{-0.5mm}\raisebox{-0.7mm}{\carbonylrotate{150}};4s==\hspace{0.5mm}\raisebox{-0.7mm}{\carbonylrotate{-150}};4==S}
{}[aj]
\put(500,200){
\tetramethylene[B]{1==\scalebox{0.5}{\put(-100,45){$\bullet$}}HO$\bf_2$C;4==CO$\bf_2$}{}
}

\dimethylene{1==CH$\bf_3$O;
2s==\sixheterov
[bdf,{B\FiveCycle(0,0){-18}[b]{2==N;4==\upnobond{\raisebox{0.8mm}{N}}{H};
3s==\rotatebox{18}{\sixfuseh[]{5s==\WedgeAsSubstX(10,18)(100,170)[10];5==S;
3s==\sixheteroh[]{3==\lmoiety{H$\bf_3$C};
4s==\sixheteroh[bdf]{6==\put(-70,0){N}
}{2==(yl);3==OCH$\bf_3$;4==CH$\bf_3$}[a]
}{1==(yl)}[abf]
}{5D==O}{f}[abc]}
}[e]}]
{}{5==(yl)}[]
}{}
\put(1150,200){\text{及び鏡像異性体}}

\sixheterov
[{e\FiveCycle(0,0){90}[ac]{3==N;5==\phantom{N};5==\hspace{0.25mm}\downnobond{\raisebox{-0.8mm}{N}}{H}}[a]}]
{4==CH$\bf_3$;
2s==\pentamethylene{1==;4==\upnobond{N}{\raisebox{-0.8mm}{H}};
5s==\sixheterov[]{1==\upnobond{N}{\raisebox{-0.8mm}{H}};2==CH$\bf_3$;4==CN;5==N}{6==(yl)}[bce]
}{1==(yl);5D==};2==S
}{}[bc]

\sixheterov
[{e\FiveCycle(0,0){90}[ac]{3==N;5==\phantom{N};5==\hspace{0.5mm}S;
4s==\sixfusev[]{4==;6==\put(-240,500){\rotatebox{-90}{\DtetrahedralS{1==NH$\bf_2$;2==H$\bf_2$N;3D==N}}}}{}{D}[abcf]
}[a]}]
{2==S;
3s==\decaheterov[]{1s==\exodoublebond{-120};7==;
2s==\trimethylene{1==;
2s==\put(-20,30){\carbonylrotate{30}}\put(20,30){\carbonylrotate{-30}};2==S;
3==NH$\bf_2$}{1==(yl)};2==N}
{1==NH$\bf_2$;6==(yl)}[abcdefgk]
}
{}[bcd]